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KMID : 0383819920390020115
Tuberculosis and Respiratory Diseases
1992 Volume.39 No. 2 p.115 ~ p.119
Transition in Mode of Onset and Progression of Tuberculosis
Kazuro Iwai
Abstract
According to the classical theory for pathogenesis of tuberculosis, the disease was
divided into two types: primary tuberculosis of so-called child type and secondary
tuberculosis of adult type. Primary tuberculosis, which develops following a primary
infection and is characterized by a lymph-hemic spread of tubercle bacilli, was further
divided into the following subtypes: 1. hilar lymph node tuberculosis, 2. early
dissemination, 3. so-called idiopathic pleurisy, 4. perforation of the hilar lymph node
lesion into the bronchial lumen with subsequent aspiration pneumonia, and 5. cavitation
of primary lung lesion. In contrast, secondary tuberculosis which develops many years
after the primary infection, shows characteristic features of isolated organ tuberculosis,
cavity formation and canalicular spread of bacilli. However, these pathogenetic patterns
are insidiously going to change or be modified, along with a decrease of tuberculosis,
probably in any country.
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